This is the most specialized feature of the bone tissue, and contains hydroxyapatite minerals. The rest of the extracellular matrix comprises organic materials that include a high abundance of collagen fibers and a small number of glycosaminoglycans. The extracellular matrix is responsible for bone tissue to demonstrate compression strength, consistency, hardness, and also elasticity. The blood system heavily irrigates the bone tissue. According to the further creation of the extracellular matrix, two types of bone tissues can be classified:
Cancellous or Trabecular: Here the bone tissues have large spaces and provide a loose or spongy appearance.
Compactor Cortical: In this case, the extracellular matrix is normally dense, and empty cavities can’t be formed. At the microscopic level, there are three types of bone tissues, depends on the organization of the collagen fiber:
Non-laminar: It is made up of collagen fibers that are interwoven.
Laminar: It has parallel collagen fibers associated with bundles.
Concentric Laminar: In this type, the collagen fibers develop the concentric rings.
These are also known as spongy spaces and got large inner spaces called vascular cavities. The hematopoietic cells and blood vessels occupied these cavities. The trabeculae are the walls of vascular cavities and have got the collagen fibers which are arranged in lamellae or intertwined forms. During the formation of bones, the woven trabecular bone is first developed and known as the primary bone, and later replaced by the secondary bone. The other two variations of secondary bones are compact bones and trabecular bones.
This type of bone has not got any vascular cavities, and the extracellular matrix is placed into the bone lamellae, which can be arranged straight and parallel or concentrically. In osteonic compact bone, the blood vessels travel through the channel known as the Haversian canal. The compact and spongy bones’ inner surface is connected by the connective tissue known as endosteum containing osteogenic cells, osteoblasts, and osteoclasts.
By this process,the bone is formed, and it must recognize between the bone cell origin and the way through which bones are formed. Embryo is having the three cell lineages that differentiate into bone cells:
Paraxial Mesoderm Cells: It offers animals a vertebrate, some parts of the skull, and face bones.
Lateral Mesoderm Cells: These cells form the bones of the limbs in animals.
Neural Crest Cells: These cells forms some of the skulls as well as face bones.
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