The increase in the hydration level of the body is also maintained by the kidneys by eliminating dilute urine. Diuresis is when the kidneys produce a large amount of urine due to ingestion of excessive fluid. The blood composition determines the absorption of water from the blood; therefore, the urine is dependent on the blood volume. The kidneys detect the volume of the blood through some protein receptors by the pressure of the blood. Thus, if the blood volume is low, the kidneys start to secrete an enzyme named rennin. Rennin activates another hormone, angiotensin, which in turn stimulates the restoration of the blood volume through the hypothalamus, the adrenal glands, and the surrounding muscles to the arteries. These stimulations again induce the kidneys to reabsorb the electrolytes from the already absorbed fluid. This enables the water to return to the blood to maintain its volume, and the urine becomes concentrated. Angiotensin also stimulates the hypothalamus to activate the body’s thirst mechanism so that one can feel the need for water and consume it. The absorption of the water through the renal tubules is also dependent on the antidiuretic hormone or vasopressin. The hypothalamus releases this hormone when there is an increase in the blood plasma concentration.
Effect of Water Concentration on Blood Volume
The adrenal glands have sensitivity towards the fluid concentration of the body. The lower concentration of fluid in the blood plasma results in the reduced sodium level and increased potassium level. The adrenal glands can detect this change in the concentration of the blood. As a result, the adrenal glands secrete the hormone aldosterone, which stimulates the reabsorption of sodium. The regulation of water concentration in the body also controls the electrolyte balance in the body. The regulation of water and electrolytes maintains homeostasis in a coordinated manner in a healthy person, but the persons with heart diseases or heart failure, indicate the reabsorption of water and sodium by the kidneys, thus increasing blood pressure. In such conditions, diuretics are given to the patients to minimize the renal response.
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